2JKU

Crystal structure of the N-terminal region of the biotin acceptor domain of human propionyl-CoA carboxylase

Summary for 2JKU

Entry DOI	10.2210/pdb2jku/pdb
Related	2CQY
Descriptor	PROPIONYL-COA CARBOXYLASE ALPHA CHAIN, MITOCHONDRIAL, TETRAETHYLENE GLYCOL (3 entities in total)
Functional Keywords	ligase, biotin, atp-binding, disease mutation, nucleotide-binding, mitochondrion, phosphoprotein, transit peptide
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	10328.70
Authors	Healy, S.,Yue, W.W.,Kochan, G.,Pilka, E.S.,Murray, J.W.,Roos, A.K.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.,Wikstrom, M.,Edwards, A.,Bountra, C.,Gravel, R.A.,Oppermann, U. (deposition date: 2008-08-30, release date: 2008-09-09, Last modification date: 2023-12-13)
Primary citation	Healy, S.,McDonald, M.K.,Wu, X.,Yue, W.W.,Kochan, G.,Oppermann, U.,Gravel, R.A. Structural impact of human and Escherichia coli biotin carboxyl carrier proteins on biotin attachment. Biochemistry, 49:4687-4694, 2010 Cited by PubMed: 20443544 DOI: 10.1021/bi901612y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation