2JKU

Crystal structure of the N-terminal region of the biotin acceptor domain of human propionyl-CoA carboxylase

2JKU の概要

• エントリーDOI: 10.2210/pdb2jku/pdb
• 関連するPDBエントリー: 2CQY
• 分子名称: PROPIONYL-COA CARBOXYLASE ALPHA CHAIN, MITOCHONDRIAL, TETRAETHYLENE GLYCOL (3 entities in total)
• 機能のキーワード: ligase, biotin, atp-binding, disease mutation, nucleotide-binding, mitochondrion, phosphoprotein, transit peptide
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 10328.70

構造登録者

Healy, S.,Yue, W.W.,Kochan, G.,Pilka, E.S.,Murray, J.W.,Roos, A.K.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.,Wikstrom, M.,Edwards, A.,Bountra, C.,Gravel, R.A.,Oppermann, U. (登録日: 2008-08-30, 公開日: 2008-09-09, 最終更新日: 2023-12-13)

• 主引用文献: Healy, S.,McDonald, M.K.,Wu, X.,Yue, W.W.,Kochan, G.,Oppermann, U.,Gravel, R.A.; Structural impact of human and Escherichia coli biotin carboxyl carrier proteins on biotin attachment.; Biochemistry, 49:4687-4694, 2010; PubMed: 20443544; DOI: 10.1021/bi901612y

実験手法

X-RAY DIFFRACTION (1.5 Å)