2JK9

The structure of splA-ryanodine receptor domain and SOCS box containing 1 in complex with a PAR-4 peptide

Summary for 2JK9

Entry DOI	10.2210/pdb2jk9/pdb
Descriptor	SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 1, PRKC APOPTOSIS WT1 REGULATOR PROTEIN (3 entities in total)
Functional Keywords	apoptosis, transcription regulation, transcription
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Cytoplasm (Probable): Q96BD6 Cytoplasm: Q96IZ0
Total number of polymer chains	2
Total formula weight	25507.79
Authors	Filippakopoulos, P.,Bullock, A.,Keates, T.,Savitsky, P.,Murray, J.W.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Wickstroem, M.,Bountra, C.,Knapp, S. (deposition date: 2008-08-22, release date: 2008-09-16, Last modification date: 2023-12-13)
Primary citation	Filippakopoulos, P.,Low, A.,Sharpe, T.D.,Uppenberg, J.,Yao, S.,Kuang, Z.,Savitsky, P.,Lewis, R.S.,Nicholson, S.E.,Norton, R.S.,Bullock, A. Structural Basis for Par-4 Recognition by the Spry Domain-and Socs Box-Containing Proteins Spsb1, Spsb2, and Spsb4. J.Mol.Biol., 401:389-, 2010 Cited by PubMed: 20561531 DOI: 10.1016/J.JMB.2010.06.017 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.79 Å)

Structure validation