2JHR

Crystal structure of myosin-2 motor domain in complex with ADP- metavanadate and pentabromopseudilin

Summary for 2JHR

Entry DOI	10.2210/pdb2jhr/pdb
Related	1D0X 1D0Y 1D0Z 1D1A 1D1B 1D1C 1FMV 1FMW 1G8X 1JWY 1JX2 1LVK 1MMA 1MMD 1MMG 1MMN 1MND 1MNE 1Q5G 1VOM 1W9I 1W9J 1W9K 1W9L 1YV3 2AKA 2JJ9
Descriptor	MYOSIN-2 HEAVY CHAIN, ADP METAVANADATE, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	contractile protein, cytoplasm, allosteric, methylation, coiled coil, atp-binding, motor protein, actin-binding, phosphoprotein, calmodulin-binding, nucleotide-binding
Biological source	DICTYOSTELIUM DISCOIDEUM (SLIME MOLD)
Cellular location	Cytoplasm, cell cortex: P08799
Total number of polymer chains	1
Total formula weight	91119.68
Authors	Fedorov, R.,Boehl, M.,Tsiavaliaris, G.,Hartmann, F.K.,Baruch, P.,Brenner, B.,Martin, R.,Knoelker, H.J.,Gutzeit, H.O.,Manstein, D.J. (deposition date: 2008-03-25, release date: 2009-01-13, Last modification date: 2023-12-13)
Primary citation	Fedorov, R.,Bohl, M.,Tsiavaliaris, G.,Hartmann, F.K.,Taft, M.H.,Baruch, P.,Brenner, B.,Martin, R.,Knolker, H.,Gutzeit, H.O.,Manstein, D.J. The Mechanism of Pentabromopseudilin Inhibition of Myosin Motor Activity. Nat.Struct.Mol.Biol., 16:80-, 2009 Cited by PubMed: 19122661 DOI: 10.1038/NSMB.1542 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation