2JGY

The crystal structure of human orotidine-5'-decarboxylase domain of human uridine monophosphate synthetase (UMPS)

2JGY の概要

• エントリーDOI: 10.2210/pdb2jgy/pdb
• 分子名称: UMP SYNTHASE (2 entities in total)
• 機能のキーワード: transferase, glycosyltransferase, alternative splicing, lyase, polymorphism, decarboxylase, disease mutation, tim barrel dimer, orotidine-5'-decarboxylase, multifunctional enzyme, pyrimidine biosynthesis
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 61262.46

構造登録者

Moche, M.,Ogg, D.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Dahlgren, L.G.,Edwards, A.,Ericsson, U.B.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg-Schiavone, L.,Johansson, I.,Karlberg, T.,Kosinska, U.,Kotenyova, T.,Lehtio, L.,Nilsson, M.E.,Nyman, T.,Persson, C.,Sagemark, J.,Stenmark, P.,Sundstrom, M.,Uppenberg, J.,Upsten, M.,Thorsell, A.G.,van den Berg, S.,Weigelt, J.,Nordlund, P.,Structural Genomics Consortium (SGC) (登録日: 2007-02-16, 公開日: 2007-03-06, 最終更新日: 2023-12-13)

• 主引用文献: Moche, M.,Flodin, S.,Nyman, T.,Stenmark, P.,Nordlund, P.; The Crystal Structure of Human Orotidine-5'-Decarboxylase Domain of Human Uridine Monophosphate Synthetase (Umps); To be Published,

実験手法

X-RAY DIFFRACTION (1.95 Å)