2JGB

Structure of human eIF4E homologous protein 4EHP with m7GTP

Summary for 2JGB

DescriptorEUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 2, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 1, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
Functional Keywordsphosphorylation, initiation factor, 4ehp, eif4e, rna-binding, acetylation, cap-binding, eukaryotic initiation factor, protein synthesis inhibitor, translation, protein biosynthesis, translation regulation
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains2
Total molecular weight25183.57
Authors
Cameron, A.D.,Rosettani, P.,Knapp, S.,Vismara, M.G.,Rusconi, L. (deposition date: 2007-02-12, release date: 2007-02-27, Last modification date: 2018-03-28)
Primary citation
Rosettani, P.,Knapp, S.,Vismara, M.G.,Rusconi, L.,Cameron, A.D.
Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms.
J. Mol. Biol., 368:691-705, 2007
PubMed: 17368478 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2007.02.019
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.7 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers702.2%11.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2jgb
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Molmil generated image of 2jgb
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Molmil generated image of 2jgb
rotated about y axis by 90°