2JGB
Structure of human eIF4E homologous protein 4EHP with m7GTP
Summary for 2JGB
Entry DOI | 10.2210/pdb2jgb/pdb |
Descriptor | EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 2, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 1, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | phosphorylation, initiation factor, 4ehp, eif4e, rna-binding, acetylation, cap-binding, eukaryotic initiation factor, protein synthesis inhibitor, translation, protein biosynthesis, translation regulation |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 2 |
Total formula weight | 25183.57 |
Authors | Cameron, A.D.,Rosettani, P.,Knapp, S.,Vismara, M.G.,Rusconi, L. (deposition date: 2007-02-12, release date: 2007-02-27, Last modification date: 2023-12-13) |
Primary citation | Rosettani, P.,Knapp, S.,Vismara, M.G.,Rusconi, L.,Cameron, A.D. Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms. J. Mol. Biol., 368:691-705, 2007 Cited by PubMed: 17368478DOI: 10.1016/j.jmb.2007.02.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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