2JFM

CRYSTAL STRUCTURE OF HUMAN STE20-LIKE KINASE (UNLIGANDED FORM)

Summary for 2JFM

Entry DOI	10.2210/pdb2jfm/pdb
Related	2J51 2JA0 2JFL
Descriptor	STE20-LIKE SERINE-THREONINE KINASE, 1,2-ETHANEDIOL (3 entities in total)
Functional Keywords	transferase, serine/threonine-protein kinase, atp-binding, phosphorylation, muscle development, kinase, apoptosis, germinal centre kinase, serine- threonine kinase 2, nucleotide-binding, serine-threonine-protein kinase
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm : Q9H2G2
Total number of polymer chains	1
Total formula weight	37366.19
Authors	Pike, A.C.W.,Rellos, P.,Fedorov, O.,Keates, T.,Salah, E.,Savitsky, P.,Papagrigoriou, E.,Bunkoczi, G.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Weigelt, J.,Sundstrom, M.,Knapp, S. (deposition date: 2007-02-02, release date: 2007-02-27, Last modification date: 2018-01-24)
Primary citation	Pike, A.C.W.,Rellos, P.,Niesen, F.H.,Turnbull, A.,Oliver, A.W.,Parker, S.A.,Turk, B.E.,Pearl, L.H.,Knapp, S. Activation Segment Dimerization: A Mechanism for Kinase Autophosphorylation of Non-Consensus Sites. Embo J., 27:704-, 2008 Cited by PubMed: 18239682 DOI: 10.1038/EMBOJ.2008.8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.85 Å)

Structure validation