2JFG

Crystal structure of MurD ligase in complex with UMA and ADP

2JFG の概要

• エントリーDOI: 10.2210/pdb2jfg/pdb
• 関連するPDBエントリー: 1E0D 1EEH 1UAG 2JFF 2JFH 2UAG 3UAG 4UAG
• 分子名称: UDP-N-ACETYLMURAMOYLALANINE--D-GLUTAMATE LIGASE, URIDINE-5'-DIPHOSPHATE-N-ACETYLMURAMOYL-L-ALANINE, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• 機能のキーワード: nucleotide-binding, peptidoglycan synthesis, murd ligase, atp-binding, cell division, uma, adp, ligase, cell wall, cell shape, cell cycle
• 由来する生物種: ESCHERICHIA COLI
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 49253.16

構造登録者

Kotnik, M.,Humljan, J.,Contreras-Martel, C.,Oblak, M.,Kristan, K.,Herve, M.,Blanot, D.,Urleb, U.,Gobec, S.,Dessen, A.,Solmajer, T. (登録日: 2007-02-01, 公開日: 2007-05-15, 最終更新日: 2023-12-13)

• 主引用文献: Kotnik, M.,Humljan, J.,Contreras-Martel, C.,Oblak, M.,Kristan, K.,Herve, M.,Blanot, D.,Urleb, U.,Gobec, S.,Dessen, A.,Solmajer, T.; Structural and functional characterization of enantiomeric glutamic acid derivatives as potential transition state analogue inhibitors of MurD ligase.; J. Mol. Biol., 370:107-115, 2007; PubMed: 17507028; DOI: 10.1016/j.jmb.2007.04.048

実験手法

X-RAY DIFFRACTION (1.52 Å)