2JET

Crystal structure of a trypsin-like mutant (S189D , A226G) chymotrypsin.

Summary for 2JET

• Entry DOI: 10.2210/pdb2jet/pdb
• Related: 1KDQ
• Descriptor: CHYMOTRYPSINOGEN B CHAIN A, CHYMOTRYPSINOGEN B CHAIN B, CHYMOTRYPSINOGEN B CHAIN C, ... (4 entities in total)
• Functional Keywords: substrate specificity, zymogen, protease, hydrolase, digestion, serine protease, protein engineering
• Biological source: RATTUS NORVEGICUS (RAT); More
• Total number of polymer chains: 3
• Total formula weight: 25679.06

Authors

Jelinek, B.,Katona, G.,Fodor, K.,Venekei, I.,Graf, L. (deposition date: 2007-01-22, release date: 2007-09-18, Last modification date: 2023-12-13)

• Primary citation: Jelinek, B.,Katona, G.,Fodor, K.,Venekei, I.,Graf, L.; The Crystal Structure of a Trypsin-Like Mutant Chymotrypsin: The Role of Position 226 in the Activity and Specificity of S189D Chymotrypsin.; Protein J., 27:79-, 2008; PubMed: 17805946; DOI: 10.1007/S10930-007-9110-3

Experimental method

X-RAY DIFFRACTION (2.2 Å)