2JED

The crystal structure of the kinase domain of the protein kinase C theta in complex with NVP-XAA228 at 2.32A resolution.

Summary for 2JED

• Entry DOI: 10.2210/pdb2jed/pdb
• Related: 1XJD
• Descriptor: PROTEIN KINASE C THETA, 3-(8-DIMETHYLAMINOMETHYL-6,7,8,9-TETRAHYDRO-PYRIDO[1,2-A]INDOL-10-YL)-4-(1-METHYL-1H-INDOL-3-YL)-PYRROLE-2,5-DIONE, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
• Functional Keywords: phosphorylation, nucleotide-binding, serine/threonine-protein kinase, transferase, atp-binding, polymorphism, metal-binding, zinc, kinase, pkc theta, magnesium, zinc-finger, alternative splicing, phorbol-ester binding
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 2
• Total formula weight: 84671.20

Authors

Stark, W.,Bitsch, F.,Berner, A.,Buelens, F.,Graff, P.,Depersin, H.,Geiser, M.,Knecht, R.,Rahuel, J.,Rummel, G.,Schlaeppi, J.M.,Schmitz, R.,Strauss, A.,Wagner, J. (deposition date: 2007-01-16, release date: 2008-02-05, Last modification date: 2023-12-13)

• Primary citation: Stark, W.,Bitsch, F.,Berner, A.,Buelens, F.,Graff, P.,Depersin, H.,Fendrich, G.,Geiser, M.,Knecht, R.,Rahuel, J.,Rummel, G.,Schlaeppi, J.M.,Schmitz, R.,Strauss, A.,Wagner, J.; The Crystal Structure of the Kinase Domain of the Protein Kinase C Theta in Complex with Nvp-Xaa228; To be Published,

Experimental method

X-RAY DIFFRACTION (2.32 Å)