2JED
The crystal structure of the kinase domain of the protein kinase C theta in complex with NVP-XAA228 at 2.32A resolution.
2JED の概要
エントリーDOI | 10.2210/pdb2jed/pdb |
関連するPDBエントリー | 1XJD |
分子名称 | PROTEIN KINASE C THETA, 3-(8-DIMETHYLAMINOMETHYL-6,7,8,9-TETRAHYDRO-PYRIDO[1,2-A]INDOL-10-YL)-4-(1-METHYL-1H-INDOL-3-YL)-PYRROLE-2,5-DIONE, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total) |
機能のキーワード | phosphorylation, nucleotide-binding, serine/threonine-protein kinase, transferase, atp-binding, polymorphism, metal-binding, zinc, kinase, pkc theta, magnesium, zinc-finger, alternative splicing, phorbol-ester binding |
由来する生物種 | HOMO SAPIENS (HUMAN) |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 84671.20 |
構造登録者 | Stark, W.,Bitsch, F.,Berner, A.,Buelens, F.,Graff, P.,Depersin, H.,Geiser, M.,Knecht, R.,Rahuel, J.,Rummel, G.,Schlaeppi, J.M.,Schmitz, R.,Strauss, A.,Wagner, J. (登録日: 2007-01-16, 公開日: 2008-02-05, 最終更新日: 2023-12-13) |
主引用文献 | Stark, W.,Bitsch, F.,Berner, A.,Buelens, F.,Graff, P.,Depersin, H.,Fendrich, G.,Geiser, M.,Knecht, R.,Rahuel, J.,Rummel, G.,Schlaeppi, J.M.,Schmitz, R.,Strauss, A.,Wagner, J. The Crystal Structure of the Kinase Domain of the Protein Kinase C Theta in Complex with Nvp-Xaa228 To be Published, |
実験手法 | X-RAY DIFFRACTION (2.32 Å) |
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