2JED

The crystal structure of the kinase domain of the protein kinase C theta in complex with NVP-XAA228 at 2.32A resolution.

2JED の概要

• エントリーDOI: 10.2210/pdb2jed/pdb
• 関連するPDBエントリー: 1XJD
• 分子名称: PROTEIN KINASE C THETA, 3-(8-DIMETHYLAMINOMETHYL-6,7,8,9-TETRAHYDRO-PYRIDO[1,2-A]INDOL-10-YL)-4-(1-METHYL-1H-INDOL-3-YL)-PYRROLE-2,5-DIONE, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
• 機能のキーワード: phosphorylation, nucleotide-binding, serine/threonine-protein kinase, transferase, atp-binding, polymorphism, metal-binding, zinc, kinase, pkc theta, magnesium, zinc-finger, alternative splicing, phorbol-ester binding
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 84671.20

構造登録者

Stark, W.,Bitsch, F.,Berner, A.,Buelens, F.,Graff, P.,Depersin, H.,Geiser, M.,Knecht, R.,Rahuel, J.,Rummel, G.,Schlaeppi, J.M.,Schmitz, R.,Strauss, A.,Wagner, J. (登録日: 2007-01-16, 公開日: 2008-02-05, 最終更新日: 2024-10-23)

• 主引用文献: Stark, W.,Bitsch, F.,Berner, A.,Buelens, F.,Graff, P.,Depersin, H.,Fendrich, G.,Geiser, M.,Knecht, R.,Rahuel, J.,Rummel, G.,Schlaeppi, J.M.,Schmitz, R.,Strauss, A.,Wagner, J.; The Crystal Structure of the Kinase Domain of the Protein Kinase C Theta in Complex with Nvp-Xaa228; To be Published,

実験手法

X-RAY DIFFRACTION (2.32 Å)