2JE5
STRUCTURAL AND MECHANISTIC BASIS OF PENICILLIN BINDING PROTEIN INHIBITION BY LACTIVICINS
Summary for 2JE5
Entry DOI | 10.2210/pdb2je5/pdb |
Related | 2BG1 2BG3 2BG4 2FFF 2JCH 2JCI |
Descriptor | PENICILLIN-BINDING PROTEIN 1B, (2E)-2-{[(2S)-2-(ACETYLAMINO)-2-CARBOXYETHOXY]IMINO}PENTANEDIOIC ACID, SULFATE ION, ... (5 entities in total) |
Functional Keywords | peptidoglycan synthesis multifunctional enzyme, cell wall, peptidoglycan, gamma lactam antibiotics, drug-binding protein |
Biological source | STREPTOCOCCUS PNEUMONIAE |
Total number of polymer chains | 2 |
Total formula weight | 157771.05 |
Authors | Macheboeuf, P.,Fisher, D.S.,Brown, T.J.,Zervosen, A.,Luxen, A.,Joris, B.,Dessen, A.,Schofield, C.J. (deposition date: 2007-01-15, release date: 2007-08-14, Last modification date: 2023-12-13) |
Primary citation | Macheboeuf, P.,Fisher, D.S.,Brown, T.J.,Zervosen, A.,Luxen, A.,Joris, B.,Dessen, A.,Schofield, C.J. Structural and Mechanistic Basis of Penicillin-Binding Protein Inhibition by Lactivicins Nat.Chem.Biol., 3:565-, 2007 Cited by PubMed: 17676039DOI: 10.1038/NCHEMBIO.2007.21 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
Download full validation report