2JCO

Crystal structure of wild type alpha-1,3 Galactosyltransferase in the absence of ligands

2JCO の概要

• エントリーDOI: 10.2210/pdb2jco/pdb
• 関連するPDBエントリー: 1FG5 1G8O 1G93 1GWV 1GWW 1GX0 1GX4 1K4V 1O7O 1O7Q 1VZT 1VZU 1VZX 2JCF 2JCJ 2JCK 2JCL
• 分子名称: N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYL TRANSFERASE, GLYCEROL (3 entities in total)
• 機能のキーワード: galactosyltransferase, transmembrane, golgi apparatus, enzyme mechanism, glycoprotein, metal-binding, signal-anchor, alpha-1, membrane, manganese, transferase, glycosyltransferase, substrate specificity
• 由来する生物種: BOS TAURUS (BOVINE)
• 細胞内の位置: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: P14769
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34182.26

構造登録者

Jamaluddin, H.,Tumbale, P.,Withers, S.G.,Acharya, K.R.,Brew, K. (登録日: 2006-12-28, 公開日: 2007-06-05, 最終更新日: 2023-12-13)

• 主引用文献: Jamaluddin, H.,Tumbale, P.,Withers, S.G.,Acharya, K.R.,Brew, K.; Conformational Changes Induced by Binding Udp-2F-Galactose to Alpha-1,3 Galactosyltransferase-Implications for Catalysis.; J.Mol.Biol., 369:1270-, 2007; PubMed: 17493636; DOI: 10.1016/J.JMB.2007.04.012

実験手法

X-RAY DIFFRACTION (2.57 Å)