2JC9

Crystal structure of Human Cytosolic 5'-Nucleotidase II in complex with adenosine

Summary for 2JC9

• Entry DOI: 10.2210/pdb2jc9/pdb
• Related: 2J2C
• Descriptor: CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: cytosolic 5-prime nucleotidase ii, gmp-imp specific nucleotidase, cn-ii, nt5c2, hydrolase, polymorphism, cytosolic purine 5-prime nucleotidase, allosteric enzyme, high km 5-prime nucleotidase
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Cytoplasm: P49902
• Total number of polymer chains: 1
• Total formula weight: 65312.22

Authors

Wallden, K.,Stenmark, P.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Edwards, A.,Ehn, M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg, S.L.,Hogbom, M.,Karlberg, T.,Kotenyova, T.,Magnusdottir, A.,Nilsson-Ehle, P.,Nyman, T.,Ogg, D.,Persson, C.,Sagemark, J.,Sundstrom, M.,Uppenberg, J.,Thorsell, A.G.,Van Den Berg, S.,Loppnau, P.,Weigelt, J.,Welin, M.,Nordlund, P. (deposition date: 2006-12-21, release date: 2007-01-02, Last modification date: 2023-12-13)

• Primary citation: Wallden, K.,Stenmark, P.,Nyman, T.,Flodin, S.,Graslund, S.,Loppnau, P.,Bianchi, V.,Nordlund, P.; Crystal Structure of Human Cytosolic 5'-Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition; J.Biol.Chem., 282:17828-, 2007; PubMed: 17405878; DOI: 10.1074/JBC.M700917200

Experimental method

X-RAY DIFFRACTION (1.5 Å)