2JC6

Crystal structure of human calmodulin-dependent protein kinase 1D

Summary for 2JC6

DescriptorCALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1D, N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE (3 entities in total)
Functional Keywordstransferase, atp-binding, nuclear protein, phosphorylation
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm  Q8IU85
Total number of polymer chains2
Total molecular weight76382.94
Authors
Primary citation
Debreczeni, J.E.,Rellos, P.,Fedorov, O.,Niesen, F.H.,Bhatia, C.,Shrestha, L.,Salah, E.,Smee, C.,Colebrook, S.,Berridge, G.,Gileadi, O.,Bunkoczi, G.,Ugochukwu, E.,Pike, A.C.W.,von Delft, F.,Knapp, S.,Sundstrom, M.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.
Crystal Structure of Human Calmodulin-Dependent Protein Kinase 1D
To be Published,
Experimental method
X-RAY DIFFRACTION (2.3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24530.7%3.2%1.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution