2JBV

Crystal structure of choline oxidase reveals insights into the catalytic mechanism

2JBV の概要

• エントリーDOI: 10.2210/pdb2jbv/pdb
• 分子名称: CHOLINE OXIDASE, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-[(4aS,10aR)-7,8-dimethyl-2,4-dioxo-1,3,4,4a,5,10a-hexahydrobenzo[g]pteridin-10(2H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate, DIMETHYL SULFOXIDE, ... (5 entities in total)
• 機能のキーワード: alcohol oxidation, flavoenyzme oxidase, covalently linked fad, arthrobacter globiformis, c4a-adduct, flavoprotein, oxidoreductase, glucose-methanol-choline oxidoreductase enzyme superfamily
• 由来する生物種: ARTHROBACTER GLOBIFORMIS
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 121532.94

構造登録者

Lountos, G.T.,Fan, F.,Gadda, G.,Orville, A.M. (登録日: 2006-12-13, 公開日: 2007-12-25, 最終更新日: 2023-12-13)

• 主引用文献: Quaye, O.,Lountos, G.T.,Fan, F.,Orville, A.M.,Gadda, G.; Role of Glu312 in Binding and Positioning of the Substrate for the Hydride Transfer Reaction in Choline Oxidase.; Biochemistry, 47:243-, 2008; PubMed: 18072756; DOI: 10.1021/BI7017943

実験手法

X-RAY DIFFRACTION (1.86 Å)