2JBA

PhoB response regulator receiver domain constitutively-active double mutant D53A and Y102C.

Summary for 2JBA

Entry DOI	10.2210/pdb2jba/pdb
Related	1B00 1GXP 1GXQ 1QQI 1ZES 2IYN 2JB9
Descriptor	PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN PHOB, SODIUM ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
Functional Keywords	transcription factor, sensory transduction, phosphate regulation, transcription regulation, activator, transport, dna-binding, constitutively-active mutant, two-component regulatory system, gene regulation, phosphate transport, activation of the pho regulon, transcription, phosphorylation, alpha/beta doubly woun fold
Biological source	ESCHERICHIA COLI More
Cellular location	Cytoplasm: P0AFJ5 P0AFJ5
Total number of polymer chains	2
Total formula weight	29019.57
Authors	Arribas-Bosacoma, R.,Ferrer-Orta, C.,Kim, S.-K.,Blanco, A.G.,Pereira, P.J.B.,Gomis-Ruth, F.X.,Wanner, B.L.,Coll, M.,Sola, M. (deposition date: 2006-12-05, release date: 2007-01-04, Last modification date: 2023-12-13)
Primary citation	Arribas-Bosacoma, R.,Kim, S.-K.,Ferrer-Orta, C.,Blanco, A.G.,Pereira, P.J.B.,Gomis-Ruth, F.X.,Wanner, B.L.,Coll, M.,Sola, M. The X-Ray Crystal Structures of Two Constitutively Active Mutants of the Escherichia Coli Phob Receiver Domain Give Insights Into Activation. J.Mol.Biol., 366:626-, 2007 Cited by PubMed: 17182055 DOI: 10.1016/J.JMB.2006.11.038 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation