2JBA

PhoB response regulator receiver domain constitutively-active double mutant D53A and Y102C.

2JBA の概要

• エントリーDOI: 10.2210/pdb2jba/pdb
• 関連するPDBエントリー: 1B00 1GXP 1GXQ 1QQI 1ZES 2IYN 2JB9
• 分子名称: PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN PHOB, SODIUM ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
• 機能のキーワード: transcription factor, sensory transduction, phosphate regulation, transcription regulation, activator, transport, dna-binding, constitutively-active mutant, two-component regulatory system, gene regulation, phosphate transport, activation of the pho regulon, transcription, phosphorylation, alpha/beta doubly woun fold
• 由来する生物種: ESCHERICHIA COLI; 詳細
• 細胞内の位置: Cytoplasm: P0AFJ5 P0AFJ5
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 29019.57

構造登録者

Arribas-Bosacoma, R.,Ferrer-Orta, C.,Kim, S.-K.,Blanco, A.G.,Pereira, P.J.B.,Gomis-Ruth, F.X.,Wanner, B.L.,Coll, M.,Sola, M. (登録日: 2006-12-05, 公開日: 2007-01-04, 最終更新日: 2023-12-13)

• 主引用文献: Arribas-Bosacoma, R.,Kim, S.-K.,Ferrer-Orta, C.,Blanco, A.G.,Pereira, P.J.B.,Gomis-Ruth, F.X.,Wanner, B.L.,Coll, M.,Sola, M.; The X-Ray Crystal Structures of Two Constitutively Active Mutants of the Escherichia Coli Phob Receiver Domain Give Insights Into Activation.; J.Mol.Biol., 366:626-, 2007; PubMed: 17182055; DOI: 10.1016/J.JMB.2006.11.038

実験手法

X-RAY DIFFRACTION (1.45 Å)