2JAH
Biochemical and structural analysis of the Clavulanic acid dehydeogenase (CAD) from Streptomyces clavuligerus
Summary for 2JAH
Entry DOI | 10.2210/pdb2jah/pdb |
Descriptor | CLAVULANIC ACID DEHYDROGENASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total) |
Functional Keywords | short-chain dehydrogenase/reductase, lactamase inhibitor, antibiotic biosynthesis, nadph, oxidoreductase, clavulanic acid |
Biological source | STREPTOMYCES CLAVULIGERUS |
Total number of polymer chains | 4 |
Total formula weight | 109723.12 |
Authors | MacKenzie, A.K.,Kershaw, N.J.,Hernandez, H.,Robinson, C.V.,Schofield, C.J.,Andersson, I. (deposition date: 2006-11-28, release date: 2007-02-20, Last modification date: 2011-07-13) |
Primary citation | Mackenzie, A.K.,Kershaw, N.J.,Hernandez, H.,Robinson, C.V.,Schofield, C.J.,Andersson, I. Clavulanic Acid Dehydrogenase: Structural and Biochemical Analysis of the Final Step in the Biosynthesis of the Beta-Lactamase Inhibitor Clavulanic Acid Biochemistry, 46:1523-, 2007 Cited by PubMed: 17279617DOI: 10.1021/BI061978X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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