2JAH

Biochemical and structural analysis of the Clavulanic acid dehydeogenase (CAD) from Streptomyces clavuligerus

Summary for 2JAH

Entry DOI	10.2210/pdb2jah/pdb
Descriptor	CLAVULANIC ACID DEHYDROGENASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
Functional Keywords	short-chain dehydrogenase/reductase, lactamase inhibitor, antibiotic biosynthesis, nadph, oxidoreductase, clavulanic acid
Biological source	STREPTOMYCES CLAVULIGERUS
Total number of polymer chains	4
Total formula weight	109723.12
Authors	MacKenzie, A.K.,Kershaw, N.J.,Hernandez, H.,Robinson, C.V.,Schofield, C.J.,Andersson, I. (deposition date: 2006-11-28, release date: 2007-02-20, Last modification date: 2011-07-13)
Primary citation	Mackenzie, A.K.,Kershaw, N.J.,Hernandez, H.,Robinson, C.V.,Schofield, C.J.,Andersson, I. Clavulanic Acid Dehydrogenase: Structural and Biochemical Analysis of the Final Step in the Biosynthesis of the Beta-Lactamase Inhibitor Clavulanic Acid Biochemistry, 46:1523-, 2007 Cited by PubMed: 17279617 DOI: 10.1021/BI061978X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation