2J6L

Structure of aminoadipate-semialdehyde dehydrogenase

2J6L の概要

• エントリーDOI: 10.2210/pdb2j6l/pdb
• 分子名称: ALDEHYDE DEHYDROGENASE FAMILY 7 MEMBER A1, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, BROMIDE ION, ... (5 entities in total)
• 機能のキーワード: aldehyde dehydrogenase, nad, reductase, oxidoreductase, lysine catabolism
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Mitochondrion . Isoform 2: Cytoplasm, cytosol: P49419
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 440062.82

構造登録者

Bunkoczi, G.,Guo, K.,Debreczeni, J.E.,Smee, C.,Arrowsmith, C.,Edwards, A.,Sundstrom, M.,Weigelt, J.,von Delft, F.,Oppermann, U. (登録日: 2006-09-29, 公開日: 2006-10-12, 最終更新日: 2023-12-13)

• 主引用文献: Brocker, C.,Lassen, N.,Estey, T.,Pappa, A.,Cantore, M.,Orlova, V.V.,Chavakis, T.,Kavanagh, K.L.,Oppermann, U.,Vasiliou, V.; Aldehyde Dehydrogenase 7A1 (Aldh7A1) is a Novel Enzyme Involved in Cellular Defense Against Hyperosmotic Stress.; J.Biol.Chem., 285:18452-, 2010; PubMed: 20207735; DOI: 10.1074/JBC.M109.077925

実験手法

X-RAY DIFFRACTION (1.3 Å)