2J0V

The crystal structure of Arabidopsis thaliana RAC7-ROP9: the first RAS superfamily GTPase from the plant kingdom

2J0V の概要

• エントリーDOI: 10.2210/pdb2j0v/pdb
• 分子名称: RAC-LIKE GTP-BINDING PROTEIN ARAC7, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: nucleotide-binding protein, rop9, atrac7, membrane, palmitate, rho gtpase, abscisic acid signaling pathway, dna binding protein nucleotide- binding, arabidopsis thaliana, lipoprotein, gtp-binding, ras superfamily
• 由来する生物種: ARABIDOPSIS THALIANA (MOUSE-EAR CRESS)
• 細胞内の位置: Membrane; Lipid-anchor: O82480
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 95405.80

構造登録者

Sormo, C.G.,Leiros, I.,Brembu, T.,Winge, P.,Os, V.,Bones, A.M. (登録日: 2006-08-07, 公開日: 2006-10-04, 最終更新日: 2023-12-13)

主引用文献

Sormo, C.G.,Leiros, I.,Brembu, T.,Winge, P.,Os, V.,Bones, A.M.
The Crystal Structure of Arabidopsis Thaliana Rac7/Rop9: The First Ras Superfamily Gtpase from the Plant Kingdom.
Phytochemistry, 67:2332-, 2006

PubMed Abstract: Arabidopsis thaliana RAC/ROP GTPases constitute a plant specific Rho GTPase family in the RAS superfamily, which has been implicated in numerous pivotal signalling cascades in plants. Research has shown that plants in some cases have evolved different modes of regulating Rho GTPase activity as compared to the equivalent systems in animals and yeast. In order to gain structural insight into plant signaling at the molecular level, we have determined the first crystal structure of a RAC-like GTPase belonging to the RAS superfamily from the plant kingdom. The structure of AtRAC7/ROP9 bound to GDP was solved at a resolution of 1.78 A. We have found that the structure of plant Rho GTPases is based upon a conserved G-domain architecture, but structural differences were found concerning the insert region and switch II region of the protein.

PubMed: 17005216
DOI: 10.1016/J.PHYTOCHEM.2006.08.011

実験手法

X-RAY DIFFRACTION (1.78 Å)