2IYO

Structural characterization of a bacterial 6PDH reveals aspects of specificity, mechanism and mode of inhibition

2IYO の概要

• エントリーDOI: 10.2210/pdb2iyo/pdb
• 関連するPDBエントリー: 2IYP 2IZ0 2IZ1
• 分子名称: 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING, 6-PHOSPHOGLUCONIC ACID, CACODYLATE ION, ... (4 entities in total)
• 機能のキーワード: oxidoreductase, 6-phosphogluconate dehydrogenase, nadp, pentose shunt, gluconate utilization
• 由来する生物種: LACTOCOCCUS LACTIS
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 52914.34

構造登録者

Sundaramoorthy, R.,Iulek, J.,Hunter, W.N. (登録日: 2006-07-21, 公開日: 2007-01-23, 最終更新日: 2023-12-13)

• 主引用文献: Sundaramoorthy, R.,Iulek, J.,Barrett, M.P.,Bidet, O.,Ruda, G.F.,Gilbert, I.H.,Hunter, W.N.; Crystal Structures of a Bacterial 6-Phosphogluconate Dehydrogenase Reveal Aspects of Specificity, Mechanism and Mode of Inhibition by Analogues of High-Energy Reaction Intermediates.; FEBS J., 274:275-, 2007; PubMed: 17222187; DOI: 10.1111/J.1742-4658.2006.05585.X

実験手法

X-RAY DIFFRACTION (2.4 Å)