2IYB

Structure of complex between the 3rd LIM domain of TES and the EVH1 domain of Mena

Summary for 2IYB

• Entry DOI: 10.2210/pdb2iyb/pdb
• Descriptor: PROTEIN ENABLED HOMOLOG, TESTIN, ZINC ION, ... (4 entities in total)
• Functional Keywords: lim domain, sh3-binding, tumour supressor lim domain evh1 domain cell motility, phosphorylation, cytoskeleton, actin-binding, metal-binding
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Cytoplasm: Q8N8S7 Q9UGI8
• Total number of polymer chains: 8
• Total formula weight: 81285.11

Authors

Briggs, D.C.,McDonald, N.Q. (deposition date: 2006-07-14, release date: 2007-10-16, Last modification date: 2023-12-13)

• Primary citation: Boeda, B.,Briggs, D.C.,Higgins, T.,Garvalov, B.K.,Fadden, A.J.,McDonald, N.Q.,Way, M.; Tes, a specific Mena interacting partner, breaks the rules for EVH1 binding.; Mol. Cell, 28:1071-1082, 2007; PubMed: 18158903; DOI: 10.1016/j.molcel.2007.10.033

Experimental method

X-RAY DIFFRACTION (2.35 Å)