2IPU

PFA1 Fab fragment complexed with Abeta 1-8 peptide

Summary for 2IPU

• Entry DOI: 10.2210/pdb2ipu/pdb
• Related: 2IPT 2IQ9 2IQA 2IQB
• Descriptor: IgG2a Fab fragment Heavy Chain, IgG2a Fab fragment Light Chain Kappa, abeta 1-8 peptide, ... (6 entities in total)
• Functional Keywords: wwddd, cdr, abeta, immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 6
• Total formula weight: 99169.57

Authors

Gardberg, A.S.,Dealwis, C. (deposition date: 2006-10-12, release date: 2007-10-09, Last modification date: 2023-08-30)

• Primary citation: Gardberg, A.S.,Dice, L.T.,Ou, S.,Rich, R.L.,Helmbrecht, E.,Ko, J.,Wetzel, R.,Myszka, D.G.,Patterson, P.H.,Dealwis, C.; Molecular basis for passive immunotherapy of Alzheimer's disease; Proc.Natl.Acad.Sci.Usa, 104:15659-15664, 2007; PubMed: 17895381; DOI: 10.1073/pnas.0705888104

Experimental method

X-RAY DIFFRACTION (1.65 Å)