2IMB
Clostridium botulinum Neurotoxin Serotype A Light Chain Inhibited by L-arginine hydroxamate
Summary for 2IMB
Entry DOI | 10.2210/pdb2imb/pdb |
Related | 2ILP 2IMA 2IMC |
Descriptor | Botulinum neurotoxin A light-chain, ZINC ION, N-HYDROXY-L-ARGININAMIDE, ... (4 entities in total) |
Functional Keywords | clostridium botulinum neurotoxin serotype a, protease inhibitors, substrate specificity, substrate switching, hydrolase |
Biological source | Clostridium botulinum |
Total number of polymer chains | 2 |
Total formula weight | 102143.80 |
Authors | Silvaggi, N.R.,Allen, K.N. (deposition date: 2006-10-04, release date: 2007-06-05, Last modification date: 2024-02-21) |
Primary citation | Silvaggi, N.R.,Boldt, G.E.,Hixon, M.S.,Kennedy, J.P.,Tzipori, S.,Janda, K.D.,Allen, K.N. Structures of Clostridium botulinum Neurotoxin Serotype A Light Chain Complexed with Small-Molecule Inhibitors Highlight Active-Site Flexibility. Chem.Biol., 14:533-542, 2007 Cited by PubMed: 17524984DOI: 10.1016/j.chembiol.2007.03.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.41 Å) |
Structure validation
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