2ILP
Clostridium botulinum Serotype A Light Chain inhibited by 4-chlorocinnamic hydroxamate
Summary for 2ILP
Entry DOI | 10.2210/pdb2ilp/pdb |
Descriptor | Botulinum neurotoxin A light-chain, ZINC ION, PHOSPHATE ION, ... (5 entities in total) |
Functional Keywords | clostridium botulinum neurotoxin, type a, substrate specificity, substrate switching, protease inhibitors, hydrolase |
Biological source | Clostridium botulinum |
Total number of polymer chains | 2 |
Total formula weight | 102255.57 |
Authors | Silvaggi, N.R.,Allen, K.N. (deposition date: 2006-10-03, release date: 2007-06-05, Last modification date: 2024-02-21) |
Primary citation | Silvaggi, N.R.,Boldt, G.E.,Hixon, M.S.,Kennedy, J.P.,Tzipori, S.,Janda, K.D.,Allen, K.N. Structures of Clostridium botulinum Neurotoxin Serotype A Light Chain Complexed with Small-Molecule Inhibitors Highlight Active-Site Flexibility. Chem.Biol., 14:533-542, 2007 Cited by PubMed: 17524984DOI: 10.1016/j.chembiol.2007.03.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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