2IHK

crystal structure of multifunctional sialyltransferase from pasteurella multocida with CMP-3F(equatorial)-Neu5Ac bound

Summary for 2IHK

• Entry DOI: 10.2210/pdb2ihk/pdb
• Related: 2IHJ
• Descriptor: Alpha-2,3/2,6-sialyltransferase/sialidase, CYTIDINE-5'-MONOPHOSPHATE-3-FLUORO-N-ACETYL-NEURAMINIC ACID (3 entities in total)
• Functional Keywords: cmp-3f(equatorial)-neu5ac sialyltransferase two-rossmann domain, transferase
• Biological source: Pasteurella multocida
• Total number of polymer chains: 1
• Total formula weight: 47099.91

Authors

Fisher, A.J.,Ni, L. (deposition date: 2006-09-26, release date: 2007-05-22, Last modification date: 2023-08-30)

• Primary citation: Ni, L.,Chokhawala, H.A.,Cao, H.,Henning, R.,Ng, L.,Huang, S.,Yu, H.,Chen, X.,Fisher, A.J.; Crystal Structures of Pasteurella multocida Sialyltransferase Complexes with Acceptor and Donor Analogues Reveal Substrate Binding Sites and Catalytic Mechanism.; Biochemistry, 46:6288-6298, 2007; PubMed: 17487984; DOI: 10.1021/bi700346w

Experimental method

X-RAY DIFFRACTION (1.9 Å)