2ICC

Extracellular Domain of CRIg

Summary for 2ICC

Entry DOI	10.2210/pdb2icc/pdb
Related	2ICE 2ICF
Descriptor	V-set and immunoglobulin domain-containing protein 4 (2 entities in total)
Functional Keywords	alternative pathway, complement receptor, ig like domain, immune system
Biological source	Homo sapiens (human)
Cellular location	Membrane ; Single-pass type I membrane protein : Q9Y279
Total number of polymer chains	1
Total formula weight	13501.17
Authors	Wiesmann, C. (deposition date: 2006-09-12, release date: 2006-11-07, Last modification date: 2017-10-18)
Primary citation	Wiesmann, C.,Katschke, K.J.,Yin, J.,Helmy, K.Y.,Steffek, M.,Fairbrother, W.J.,McCallum, S.A.,Embuscado, L.,DeForge, L.,Hass, P.E.,van Lookeren Campagne, M. Structure of C3b in complex with CRIg gives insights into regulation of complement activation. Nature, 444:217-220, 2006 Cited by PubMed: 17051150 DOI: 10.1038/nature05263 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.2 Å)

Structure validation