2I80
Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies
Summary for 2I80
Entry DOI | 10.2210/pdb2i80/pdb |
Descriptor | D-alanine-D-alanine ligase, 3-CHLORO-2,2-DIMETHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE (3 entities in total) |
Functional Keywords | protein-inhibitor complex, ligase |
Biological source | Staphylococcus aureus |
Cellular location | Cytoplasm (By similarity): Q5HEB7 |
Total number of polymer chains | 2 |
Total formula weight | 82151.38 |
Authors | Liu, S.,Chang, J.S.,Herberg, J.T.,Horng, M.-M.,Tomich, P.K.,Lin, A.H.,Marotti, K.R. (deposition date: 2006-08-31, release date: 2006-09-26, Last modification date: 2023-08-30) |
Primary citation | Liu, S.,Chang, J.S.,Herberg, J.T.,Horng, M.M.,Tomich, P.K.,Lin, A.H.,Marotti, K.R. Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies. Proc.Natl.Acad.Sci.Usa, 103:15178-15183, 2006 Cited by PubMed: 17015835DOI: 10.1073/pnas.0604905103 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.19 Å) |
Structure validation
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