2I7V
Structure of Human CPSF-73
Summary for 2I7V
Entry DOI | 10.2210/pdb2i7v/pdb |
Related | 2I7T 2I7X |
Descriptor | Cleavage and polyadenylation specificity factor 73 kDa subunit, ZINC ION, SULFATE ION, ... (4 entities in total) |
Functional Keywords | polyadenylation, metallo-b-lactamase, pre-mrna processing, artemis, v(d)j recombination, double-strand break repair, hydrolase, rna binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : Q9UKF6 |
Total number of polymer chains | 1 |
Total formula weight | 52660.61 |
Authors | Mandel, C.R.,Zhang, H.,Tong, L. (deposition date: 2006-08-31, release date: 2007-01-30, Last modification date: 2024-02-21) |
Primary citation | Mandel, C.R.,Kaneko, S.,Zhang, H.,Gebauer, D.,Vethantham, V.,Manley, J.L.,Tong, L. Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease. Nature, 444:953-956, 2006 Cited by PubMed: 17128255DOI: 10.1038/nature05363 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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