2I7B

Structure of the naturally occuring mutant of human ABO(H) Blood group B glycosyltransferase: GTB/A268T

2I7B の概要

• エントリーDOI: 10.2210/pdb2i7b/pdb
• 分子名称: alpha 1-3-galactosyltransferase, MERCURY (II) ION (3 entities in total)
• 機能のキーワード: glycosyltransferase, blood group, abo allele, hybrid allele, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34841.66

構造登録者

Letts, J.A.,Evans, S.V. (登録日: 2006-08-30, 公開日: 2007-05-22, 最終更新日: 2023-08-30)

• 主引用文献: Hosseini-Maaf, B.,Letts, J.A.,Persson, M.,Smart, E.,Lepennec, P.Y.,Hustinx, H.,Zhao, Z.,Palcic, M.M.,Evans, S.V.,Chester, M.A.,Olsson, M.L.; Structural basis for red cell phenotypic changes in newly identified, naturally occurring subgroup mutants of the human blood group B glycosyltransferase.; Transfusion, 47:864-875, 2007; PubMed: 17465952; DOI: 10.1111/j.1537-2995.2007.01203.x

実験手法

X-RAY DIFFRACTION (1.99 Å)