2I6U

Crystal Structure of Ornithine Carbamoyltransferase complexed with Carbamoyl Phosphate and L-Norvaline from Mycobacterium tuberculosis (Rv1656) at 2.2 A

2I6U の概要

• エントリーDOI: 10.2210/pdb2i6u/pdb
• 分子名称: Ornithine carbamoyltransferase, SULFATE ION, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, ... (5 entities in total)
• 機能のキーワード: mycobacterium tuberculosis, ornithine carbamyoltransferase, carbamoyl phosphate, l-norvaline, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc, transferase
• 由来する生物種: Mycobacterium tuberculosis
• 細胞内の位置: Cytoplasm (Probable): P0A5M8
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 100447.40

構造登録者

Sankaranarayanan, R.,Moradian, F.,Cherney, L.T.,Garen, C.,Cherney, M.M.,James, M.N.G.,TB Structural Genomics Consortium (TBSGC) (登録日: 2006-08-29, 公開日: 2007-06-26, 最終更新日: 2023-08-30)

• 主引用文献: Sankaranarayanan, R.,Cherney, M.M.,Cherney, L.T.,Garen, C.R.,Moradian, F.,James, M.N.; The crystal structures of ornithine carbamoyltransferase from Mycobacterium tuberculosis and its ternary complex with carbamoyl phosphate and L-norvaline reveal the enzyme's catalytic mechanism; J.Mol.Biol., 375:1052-1063, 2008; PubMed: 18062991; DOI: 10.1016/j.jmb.2007.11.025

実験手法

X-RAY DIFFRACTION (2.2 Å)