Summary for 7AQB
Entry DOI | 10.2210/pdb7aqb/pdb |
Descriptor | Mitogen-activated protein kinase 6, MAGNESIUM ION, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | mapk6, erk3, kinase, structural genomics, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 72647.87 |
Authors | Filippakopoulos, P.,Schroeder, M.,Chaikuad, A.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2020-10-20, release date: 2020-11-11, Last modification date: 2024-01-31) |
Primary citation | Schroder, M.,Filippakopoulos, P.,Schwalm, M.P.,Ferrer, C.A.,Drewry, D.H.,Knapp, S.,Chaikuad, A. Crystal Structure and Inhibitor Identifications Reveal Targeting Opportunity for the Atypical MAPK Kinase ERK3. Int J Mol Sci, 21:-, 2020 Cited by PubMed: 33114754DOI: 10.3390/ijms21217953 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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