2I19

T. Brucei farnesyl diphosphate synthase complexed with bisphosphonate

2I19 の概要

• エントリーDOI: 10.2210/pdb2i19/pdb
• 分子名称: Farnesyl pyrophosphate synthase, MAGNESIUM ION, [2-(PYRIDIN-2-YLAMINO)ETHANE-1,1-DIYL]BIS(PHOSPHONIC ACID), ... (4 entities in total)
• 機能のキーワード: protein-bisphosphonate complex, transferase
• 由来する生物種: Trypanosoma brucei
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 89661.56

構造登録者

Cao, R.,Mao, J.,Gao, Y.,Robinson, H.,Odeh, S.,Goddard, A.,Oldfield, E. (登録日: 2006-08-13, 公開日: 2006-10-17, 最終更新日: 2023-08-30)

• 主引用文献: Mao, J.,Mukherjee, S.,Zhang, Y.,Cao, R.,Sanders, J.M.,Song, Y.,Zhang, Y.,Meints, G.A.,Gao, Y.G.,Mukkamala, D.,Hudock, M.P.,Oldfield, E.; Solid-state NMR, crystallographic, and computational investigation of bisphosphonates and farnesyl diphosphate synthase-bisphosphonate complexes.; J.Am.Chem.Soc., 128:14485-14497, 2006; PubMed: 17090032; DOI: 10.1021/ja061737c

実験手法

X-RAY DIFFRACTION (2.28 Å)