2I04
X-ray crystal structure of MAGI-1 PDZ1 bound to the C-terminal peptide of HPV18 E6
Summary for 2I04
| Entry DOI | 10.2210/pdb2i04/pdb |
| Descriptor | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, peptide E6, SULFATE ION, ... (4 entities in total) |
| Functional Keywords | pdz, e6 binding, tumor suppressor, peptide binding protein |
| Biological source | Mus musculus (house mouse) More |
| Cellular location | Isoform 2: Cytoplasm (Probable). Isoform 3: Cytoplasm (Probable). Isoform 1: Nucleus (Probable): Q6RHR9 Host nucleus matrix (By similarity): P06463 |
| Total number of polymer chains | 4 |
| Total formula weight | 20239.02 |
| Authors | Chen, X.S.,Zhang, Y.,Dasgupta, J.,Banks, L.,Thomas, M. (deposition date: 2006-08-09, release date: 2007-02-20, Last modification date: 2011-07-13) |
| Primary citation | Zhang, Y.,Dasgupta, J.,Ma, R.Z.,Banks, L.,Thomas, M.,Chen, X.S. Structures of a Human Papillomavirus (HPV) E6 Polypeptide Bound to MAGUK Proteins: Mechanisms of Targeting Tumor Suppressors by a High-Risk HPV Oncoprotein. J.Virol., 81:3618-3626, 2007 Cited by PubMed: 17267502DOI: 10.1128/JVI.02044-06 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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