2I04

X-ray crystal structure of MAGI-1 PDZ1 bound to the C-terminal peptide of HPV18 E6

2I04 の概要

• エントリーDOI: 10.2210/pdb2i04/pdb
• 分子名称: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, peptide E6, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: pdz, e6 binding, tumor suppressor, peptide binding protein
• 由来する生物種: Mus musculus (house mouse); 詳細
• 細胞内の位置: Isoform 2: Cytoplasm (Probable). Isoform 3: Cytoplasm (Probable). Isoform 1: Nucleus (Probable): Q6RHR9; Host nucleus matrix (By similarity): P06463
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 20239.02

構造登録者

Chen, X.S.,Zhang, Y.,Dasgupta, J.,Banks, L.,Thomas, M. (登録日: 2006-08-09, 公開日: 2007-02-20, 最終更新日: 2011-07-13)

• 主引用文献: Zhang, Y.,Dasgupta, J.,Ma, R.Z.,Banks, L.,Thomas, M.,Chen, X.S.; Structures of a Human Papillomavirus (HPV) E6 Polypeptide Bound to MAGUK Proteins: Mechanisms of Targeting Tumor Suppressors by a High-Risk HPV Oncoprotein.; J.Virol., 81:3618-3626, 2007; PubMed: 17267502; DOI: 10.1128/JVI.02044-06

実験手法

X-RAY DIFFRACTION (2.15 Å)