2HYV
Human Annexin A2 with heparin hexasaccharide bound
Summary for 2HYV
Entry DOI | 10.2210/pdb2hyv/pdb |
Descriptor | Annexin A2, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | calcium-binding protein, membrane-binding protein, helix bundle, heparin, hexasaccharide, metal binding protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 36963.86 |
Authors | Shao, C.,Head, J.F.,Seaton, B.A. (deposition date: 2006-08-07, release date: 2006-09-05, Last modification date: 2023-09-20) |
Primary citation | Shao, C.,Zhang, F.,Kemp, M.M.,Linhardt, R.J.,Waisman, D.M.,Head, J.F.,Seaton, B.A. Crystallographic analysis of calcium-dependent heparin binding to annexin A2. J.Biol.Chem., 281:31689-31695, 2006 Cited by PubMed: 16882661DOI: 10.1074/jbc.M604502200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.42 Å) |
Structure validation
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