2HYV

Human Annexin A2 with heparin hexasaccharide bound

2HYV の概要

• エントリーDOI: 10.2210/pdb2hyv/pdb
• 分子名称: Annexin A2, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: calcium-binding protein, membrane-binding protein, helix bundle, heparin, hexasaccharide, metal binding protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36963.86

構造登録者

Shao, C.,Head, J.F.,Seaton, B.A. (登録日: 2006-08-07, 公開日: 2006-09-05, 最終更新日: 2023-09-20)

• 主引用文献: Shao, C.,Zhang, F.,Kemp, M.M.,Linhardt, R.J.,Waisman, D.M.,Head, J.F.,Seaton, B.A.; Crystallographic analysis of calcium-dependent heparin binding to annexin A2.; J.Biol.Chem., 281:31689-31695, 2006; PubMed: 16882661; DOI: 10.1074/jbc.M604502200

実験手法

X-RAY DIFFRACTION (1.42 Å)