2HRC
1.7 angstrom structure of human ferrochelatase variant R115L
Summary for 2HRC
Entry DOI | 10.2210/pdb2hrc/pdb |
Related | 2HRE |
Descriptor | Ferrochelatase, CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, ... (7 entities in total) |
Functional Keywords | heme synthesis, ferrochelatase, protoporphyrin ix, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side: P22830 |
Total number of polymer chains | 2 |
Total formula weight | 85372.93 |
Authors | Medlock, A.,Swartz, L.,Dailey, T.A.,Dailey, H.A.,Lanzilotta, W.N. (deposition date: 2006-07-20, release date: 2007-03-13, Last modification date: 2023-08-30) |
Primary citation | Medlock, A.,Swartz, L.,Dailey, T.A.,Dailey, H.A.,Lanzilotta, W.N. Substrate interactions with human ferrochelatase Proc.Natl.Acad.Sci.Usa, 104:1789-1793, 2007 Cited by PubMed: 17261801DOI: 10.1073/pnas.0606144104 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
Download full validation report