Summary for 2HMI
| Entry DOI | 10.2210/pdb2hmi/pdb |
| Descriptor | DNA (5'-D(*AP*TP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*A)-3'), SUBUNIT OF V-1 REVERSE TRANSCRIPTASE, ... (6 entities in total) |
| Functional Keywords | aids, hiv-1, rt, polymerase, immune system-dna complex, immune system/dna |
| Biological source | Human immunodeficiency virus 1 More |
| Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03366 P03366 |
| Total number of polymer chains | 6 |
| Total formula weight | 172346.97 |
| Authors | Ding, J.,Arnold, E. (deposition date: 1998-04-10, release date: 1998-10-14, Last modification date: 2021-11-03) |
| Primary citation | Ding, J.,Das, K.,Hsiou, Y.,Sarafianos, S.G.,Clark Jr., A.D.,Jacobo-Molina, A.,Tantillo, C.,Hughes, S.H.,Arnold, E. Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution. J.Mol.Biol., 284:1095-1111, 1998 Cited by PubMed: 9837729DOI: 10.1006/jmbi.1998.2208 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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