2HMD

Stereochemistry Modulates Stability of Reduced Inter-Strand Cross-Links Arising From R- and S-alpha-methyl-gamma-OH-1,N2-propano-2'-Deoxyguanine in the 5'-CpG-3' DNA Sequence

2HMD の概要

• エントリーDOI: 10.2210/pdb2hmd/pdb
• 関連するPDBエントリー: 2HLI 2HMR
• 分子名称: DNA dodecamer with interstrand cross-link (2 entities in total)
• 機能のキーワード: crotonaldehyde interstrand dna cross-link, dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 7382.89

構造登録者

Cho, Y.-J.,Kozekov, I.D.,Harris, T.M.,Rizzo, C.J.,Stone, M.P. (登録日: 2006-07-11, 公開日: 2007-03-13, 最終更新日: 2024-05-29)

• 主引用文献: Cho, Y.-J.,Kozekov, I.D.,Harris, T.M.,Rizzo, C.J.,Stone, M.P.; Stereochemistry Modulates the Stability of Reduced Interstrand Cross-Links Arising from R- and S-alpha-CH(3)-gamma-OH-1,N(2)-Propano-2'-deoxyguanosine in the 5'-CpG-3' DNA Sequence; Biochemistry, 46:2608-2621, 2007; PubMed: 17305317; DOI: 10.1021/bi061381h

実験手法

SOLUTION NMR