2HL3
Crystal structure of the A49M mutant CAP-Gly domain of human Dynactin-1 (p150-Glued) in complex with human EB1 C-terminal hexapeptide
Summary for 2HL3
Entry DOI | 10.2210/pdb2hl3/pdb |
Related | 1TXQ 2COY 2HKN 2HL3 2HL5 |
Descriptor | Dynactin-1, Microtubule-associated protein RP/EB family member 1 (3 entities in total) |
Functional Keywords | microtubule binding, dynactin, cytoskeleton associated protein, p150glued, eb1, +tip protein complex structure, eey/f-coo- sequence motif, clip-170, alpha-tubulin, structural protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm : Q14203 Cytoplasm, cytoskeleton: Q15691 |
Total number of polymer chains | 3 |
Total formula weight | 21564.84 |
Authors | Honnappa, S.,Winkler, F.K.,Steinmetz, M.O. (deposition date: 2006-07-06, release date: 2006-09-12, Last modification date: 2024-02-14) |
Primary citation | Honnappa, S.,Okhrimenko, O.,Jaussi, R.,Jawhari, H.,Jelesarov, I.,Winkler, F.K.,Steinmetz, M.O. Key interaction modes of dynamic +TIP networks. Mol.Cell, 23:663-671, 2006 Cited by PubMed: 16949363DOI: 10.1016/j.molcel.2006.07.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.03 Å) |
Structure validation
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