2HK7

Crystal structure of shikimate dehydrogenase from aquifex aeolicus in complex with mercury at 2.5 angstrom resolution

Summary for 2HK7

• Entry DOI: 10.2210/pdb2hk7/pdb
• Related: 1WXD 2EV9
• Descriptor: Shikimate dehydrogenase, MERCURY (II) ION (3 entities in total)
• Functional Keywords: shikimate pathway, shikimate dehydrogenase, drug design, oxidoreductase
• Biological source: Aquifex aeolicus
• Total number of polymer chains: 2
• Total formula weight: 61429.83

Authors

Gan, J.H.,Prabakaran, P.,Gu, Y.J.,Andrykovitch, M.,Li, Y.,Liu, H.H.,Yan, H.,Ji, X. (deposition date: 2006-07-03, release date: 2007-06-19, Last modification date: 2023-08-30)

• Primary citation: Gan, J.,Wu, Y.,Prabakaran, P.,Gu, Y.,Li, Y.,Andrykovitch, M.,Liu, H.,Gong, Y.,Yan, H.,Ji, X.; Structural and biochemical analyses of shikimate dehydrogenase AroE from Aquifex aeolicus: implications for the catalytic mechanism.; Biochemistry, 46:9513-9522, 2007; PubMed: 17649975; DOI: 10.1021/bi602601e

Experimental method

X-RAY DIFFRACTION (2.5 Å)