2HH4
NMR structure of human insulin mutant GLY-B8-D-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures
Summary for 2HH4
Entry DOI | 10.2210/pdb2hh4/pdb |
Related | 2hho |
Descriptor | insulin A chain, insulin B chain (2 entities in total) |
Functional Keywords | hormone, human insulin, mutant, hormone-growth factor complex, hormone/growth factor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 5824.62 |
Authors | Hua, Q.X.,Nakagawa, S.,Hu, S.Q.,Jia, W.,Weiss, M.A. (deposition date: 2006-06-27, release date: 2006-07-18, Last modification date: 2021-10-20) |
Primary citation | Hua, Q.X.,Nakagawa, S.,Hu, S.Q.,Jia, W.,Wang, S.,Weiss, M.A. Toward the Active Conformation of Insulin: Stereospecific modulation of a structural switch in the B chain. J.Biol.Chem., 281:24900-24909, 2006 Cited by PubMed: 16762918DOI: 10.1074/jbc.M602691200 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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