2HE8
Crystal structure of 17alpha-hydroxysteroid dehydrogenase in its apo-form
Summary for 2HE8
Entry DOI | 10.2210/pdb2he8/pdb |
Related | 2HDJ 2HE5 2HEJ |
Descriptor | Aldo-keto reductase family 1, member C21, ACETATE ION, BETA-MERCAPTOETHANOL, ... (5 entities in total) |
Functional Keywords | 17a-hsd, akr1c21, akr, aldo-keto reductase, hsd, hydroxysteroid dehydrogenase, apo-form, oxidoreductase |
Biological source | Mus musculus (house mouse) |
Total number of polymer chains | 2 |
Total formula weight | 74596.01 |
Authors | Faucher, F.,Pereira de Jesus-Tran, K.,Cantin, L.,Luu-the, V.,Labrie, F.,Breton, R. (deposition date: 2006-06-21, release date: 2006-12-05, Last modification date: 2023-12-06) |
Primary citation | Faucher, F.,Pereira de Jesus-Tran, K.,Cantin, L.,Luu-The, V.,Labrie, F.,Breton, R. Crystal Structures of Mouse 17alpha-Hydroxysteroid Dehydrogenase (Apoenzyme and Enzyme-NADP(H) Binary Complex): Identification of Molecular Determinants Responsible for the Unique 17alpha-reductive Activity of this Enzyme. J.Mol.Biol., 364:747-763, 2006 Cited by PubMed: 17034817DOI: 10.1016/j.jmb.2006.09.030 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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