Crystal structure of the 3rd PDZ domain of human discs large homologue 2, DLG2

Summary for 2HE2

DescriptorDiscs large homolog 2 (2 entities in total)
Functional Keywordsdlg2, pdz, pdz domain, signal transduction, structural genomics, structural genomics consortium, sgc, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Lipid-anchor (By similarity) Q15700
Total number of polymer chains2
Total molecular weight21353.78
Primary citation
Elkins, J.M.,Papagrigoriou, E.,Berridge, G.,Yang, X.,Phillips, C.,Gileadi, C.,Savitsky, P.,Doyle, D.A.
Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16:683-694, 2007
PubMed: 17384233 (PDB entries with the same primary citation)
DOI: 10.1110/ps.062657507
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.185201.3%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution