2HDJ
Crystal structure of human type 3 3alpha-hydroxysteroid dehydrogenase in complex with NADP(H)
Summary for 2HDJ
Entry DOI | 10.2210/pdb2hdj/pdb |
Descriptor | Aldo-keto reductase family 1 member C2, SULFATE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total) |
Functional Keywords | human 3alphahds3, aldo-keto reductase, nadph, akr, akr1c2, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm (Potential): P52895 |
Total number of polymer chains | 2 |
Total formula weight | 75820.03 |
Authors | Faucher, F.,Pereira de Jesus-Tran, K.,Cantin, L.,Luu-the, V.,Labrie, F.,Breton, R. (deposition date: 2006-06-20, release date: 2006-12-05, Last modification date: 2023-08-30) |
Primary citation | Faucher, F.,Pereira de Jesus-Tran, K.,Cantin, L.,Luu-The, V.,Labrie, F.,Breton, R. Crystal Structures of Mouse 17alpha-Hydroxysteroid Dehydrogenase (Apoenzyme and Enzyme-NADP(H) Binary Complex): Identification of Molecular Determinants Responsible for the Unique 17alpha-reductive Activity of this Enzyme. J.Mol.Biol., 364:747-763, 2006 Cited by PubMed: 17034817DOI: 10.1016/j.jmb.2006.09.030 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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