2HDJ

Crystal structure of human type 3 3alpha-hydroxysteroid dehydrogenase in complex with NADP(H)

2HDJ の概要

• エントリーDOI: 10.2210/pdb2hdj/pdb
• 分子名称: Aldo-keto reductase family 1 member C2, SULFATE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total)
• 機能のキーワード: human 3alphahds3, aldo-keto reductase, nadph, akr, akr1c2, oxidoreductase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm (Potential): P52895
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 75820.03

構造登録者

Faucher, F.,Pereira de Jesus-Tran, K.,Cantin, L.,Luu-the, V.,Labrie, F.,Breton, R. (登録日: 2006-06-20, 公開日: 2006-12-05, 最終更新日: 2023-08-30)

• 主引用文献: Faucher, F.,Pereira de Jesus-Tran, K.,Cantin, L.,Luu-The, V.,Labrie, F.,Breton, R.; Crystal Structures of Mouse 17alpha-Hydroxysteroid Dehydrogenase (Apoenzyme and Enzyme-NADP(H) Binary Complex): Identification of Molecular Determinants Responsible for the Unique 17alpha-reductive Activity of this Enzyme.; J.Mol.Biol., 364:747-763, 2006; PubMed: 17034817; DOI: 10.1016/j.jmb.2006.09.030

実験手法

X-RAY DIFFRACTION (2 Å)